Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6354445 | 1.00 | MEN1 (0.50) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL57319 | 0.85 | — | — | |
| Ethylene Glycol SCHEMBL821381 | 0.85 | TSHR (0.32) | TSHR | |
| SCHEMBL10796094 | 0.83 | TSHR (0.41) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL8607254 | 0.83 | MEN1 (0.46) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL8733484 | 0.83 | ALDH1A1 (0.31) | MEN1KMT2ATSHRALDH1A1TP53 | |
| Triethylene Glycol SCHEMBL11005553 | 0.81 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Tetraethylene Glycol SCHEMBL28555228 | 0.81 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL28472707 | 0.79 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL31235682 | 0.78 | MEN1 (0.46) | MEN1KMT2ATSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0130680-A2 | Cure to elastomers composition | LOCTITE CORPORATION (US) | 1985-01-09 | — | — | EP | claimed |
| US-4439600-A | Cure to elastomers compositions | LOCTITE CORPORATION (US) | 1984-03-27 | — | — | US | claimed |
| EP-0130680-A2 | Cure to elastomers composition | LOCTITE CORPORATION (US) | 1985-01-09 | — | — | EP | disclosed |
| US-4439600-A | Cure to elastomers compositions | LOCTITE CORPORATION (US) | 1984-03-27 | — | — | US | disclosed |
| US-3983057-A | MERCAPTO REGULATORS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-09-28 | — | — | US | disclosed |