SCHEMBL8733484

SCHEMBL8733484

O=C(OCCOC(=O)C(S)S)C(S)S

nearest known ligand 0.31

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.31
TSHR P16473 3/20 0.31
HIF1A Q16665 3/20 0.31
HSD17B10 Q99714 3/20 0.31
TP53 P04637 2/20 0.31
HPGD P15428 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
ABCB11 O95342 1/20 0.30
F2 P00734 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
KMT2A Q03164 1/20 0.30
DUSP3 P51452 1/20 0.30
PTPN5 P54829 1/20 0.30
PTPN11 Q06124 1/20 0.30
LMNA P02545 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL821381 0.91 TSHR (0.32) TSHR
SCHEMBL9346110 0.89
SCHEMBL57319 0.85
SCHEMBL10796094 0.83 TSHR (0.41) ALDH1A1TSHRMEN1KMT2A
SCHEMBL11005545 0.83 MEN1 (0.50) ALDH1A1TSHRHIF1AHSD17B10TP53
SCHEMBL5996548 0.83 ALDH1A1 (0.58) ALDH1A1TSHRHIF1AHSD17B10TP53
SCHEMBL6354445 0.83 MEN1 (0.50) ALDH1A1TSHRHIF1AHSD17B10TP53
Ethylene Glycol SCHEMBL15263237 0.81 ALDH1A1 (0.34) ALDH1A1TSHRTDP1
SCHEMBL625080 0.79 ACHE (0.40) ALDH1A1TSHRTDP1
SCHEMBL28372754 0.79 ALDH1A1 (0.56) ALDH1A1TSHRHPGDTDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118162293-A Method for separating zinc and sulfur from high-residue medicament ore pulp 中国矿业大学(北京) 2024-06-11 CN claimed
CN-115023465-B Thermoplastic resin composition 旭化成株式会社 2025-02-14 CN disclosed
CN-113227902-B Liquid photopolymer resin composition for flexographic printing 麦克德米德图像方案股份有限公司 2024-09-27 CN disclosed
CN-118162293-B Method for separating zinc and sulfur from high-residue medicament ore pulp 中国矿业大学(北京) 2024-08-02 CN disclosed
CN-118162293-A Method for separating zinc and sulfur from high-residue medicament ore pulp 中国矿业大学(北京) 2024-06-11 CN disclosed
US-11518866-B2 Peroxy ester cure of liquid prepolymer compositions ARKEMA INC. (US) 2022-12-06 US disclosed
US-20180355133-A1 PEROXY ESTER CURE OF LIQUID PREPOLYMER COMPOSITIONS ARKEMA INC. 2018-12-13 US disclosed
EP-3383940-A1 PEROXY ESTER CURE OF LIQUID PREPOLYMER COMPOSITIONS Arkema Inc. (US) 2018-10-10 EP disclosed
WO-2017095893-A1 PEROXY ESTER CURE OF LIQUID PREPOLYMER COMPOSITIONS ARKEMA INC. (US) 2017-06-08 WO disclosed
EP-0497611-B1 Biodegradable polymers, process for preparation of such polymers, and compositions containing such polymers ROHM & HAAS (US) 1998-01-07 EP disclosed
US-5264510-A Terpolymer, containing first monomer from vinyl acetate, vinyl carbonate, or vinyl ether, second one is ethylenically unsaturated monocarboxylic acid and third is an anhydride ROHM AND HAAS COMPANY (US) 1993-11-23 US disclosed
US-5191048-A Detergents ROHM & HAAS COMPANY (US) 1993-03-02 US disclosed
EP-0497611-A1 Biodegradable polymers, process for preparation of such polymers, and compositions containing such polymers ROHM AND HAAS COMPANY (US) 1992-08-05 EP disclosed
EP-0014930-B1 FLUORINE-CONTAINING POLYMER AND COMPOSITION CONTAINING SAME Daikin Kogyo Co., Ltd. (JP) 1988-05-04 EP disclosed
US-4530972-A Using free radical catalyst, iodine compound and ultraviolet light source DAIKIN KOGYO CO., LTD. (JP) 1985-07-23 US disclosed
US-4277427-A DISTRIBUTION OF RESINOUS FLAKES CONTAINING A BLOWING AGENT SUPPRESSOR ON A PRINTED, GELLED, FOAMABLE POLYMER CONGOLEUM CORPORATION (US) 1981-07-07 US disclosed
US-4267087-A Perfluoroalkyl substituted anhydrides and polyacids, and derivatives thereof CIBA-GEIGY CORPORATION (US) 1981-05-12 US disclosed
EP-0014930-A1 Fluorine-containing polymer and composition containing same Daikin Kogyo Co., Ltd. (JP) 1980-09-03 EP disclosed
US-4153590-A AMPHOTERIC SURFACTANTS FOR POLYCONDENSATE RESIN SYSTEMS CIBA-GEIGY CORPORATION (US) 1979-05-08 US disclosed
US-4058537-A SURFACTANTS CIBA-GEIGY CORPORATION (US) 1977-11-15 US disclosed