Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2792594 | 0.86 | PTGDR2 (0.39) | PTGDR2 | |
| SCHEMBL5162304 | 0.86 | PTGDR2 (0.41) | PTGDR2 | |
| SCHEMBL11002739 | 0.85 | PTGDR2 (0.40) | PTGDR2 | |
| SCHEMBL11003580 | 0.79 | PTGDR2 (0.44) | PTGDR2 | |
| SCHEMBL1846438 | 0.78 | PTGDR2 (0.45) | PTGDR2 | |
| SCHEMBL1846189 | 0.78 | MAP3K14 (0.50) | PTGDR2 | |
| SCHEMBL1843412 | 0.78 | ADRA2A (0.46) | PTGDR2HCRTR2MAPT | |
| SCHEMBL1845395 | 0.77 | PTGDR2 (0.49) | PTGDR2 | |
| SCHEMBL11001528 | 0.75 | PTGDR2 (0.41) | PTGDR2 | |
| SCHEMBL1570198 | 0.74 | PTGDR2 (0.43) | PTGDR2HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4530919-A | A 1,2,3,4-tetrahydronaphthalene carboxylic acid | PFIZER INC. (US) | 1985-07-23 | — | — | US | disclosed |
| US-4374148-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1983-02-15 | — | — | US | disclosed |
| US-4305955-A | ORAL HYPOGLYCEMIC AGENTS, CHROMAN-4-CARBOXYLIC ACID OR THIOCHROMAN-4-CARBOXYLIC ACID | PFIZER INC. (US) | 1981-12-15 | — | — | US | disclosed |