Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847468 | 0.84 | USP2 (0.42) | HCRTR2KDM4E | |
| SCHEMBL5847462 | 0.84 | USP2 (0.42) | HCRTR2KDM4E | |
| SCHEMBL5847465 | 0.84 | USP2 (0.42) | HCRTR2KDM4E | |
| SCHEMBL9150944 | 0.79 | MAP3K14 (0.47) | HCRTR2KDM4E | |
| SCHEMBL1846189 | 0.78 | MAP3K14 (0.50) | PTGDR2 | |
| SCHEMBL1846438 | 0.78 | PTGDR2 (0.45) | PTGDR2 | |
| SCHEMBL1843412 | 0.78 | ADRA2A (0.46) | PTGDR2HCRTR2 | |
| SCHEMBL1266045 | 0.77 | DRD2 (0.42) | HCRTR2 | |
| SCHEMBL29243618 | 0.77 | DRD2 (0.42) | HCRTR2 | |
| Cyanate SCHEMBL27883107 | 0.77 | PTGDR2 (0.41) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307397-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |