Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015631 | 0.78 | KMT2A (0.49) | KMT2AMEN1CYP19A1TBXAS1PRKCI | |
| SCHEMBL8337928 | 0.76 | TBXAS1 (0.54) | CYP19A1TBXAS1CYP11B1CYP11B2ALOX15 | |
| SCHEMBL31061448 | 0.74 | CYP19A1 (0.49) | CYP19A1TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL24916774 | 0.73 | CCR1 (0.52) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30201993 | 0.73 | CCR1 (0.52) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28803051 | 0.73 | CYP19A1 (0.49) | KMT2AMEN1CYP19A1TBXAS1PRKCI | |
| SCHEMBL9323999 | 0.72 | CYP11B1 (0.58) | KMT2AMEN1CYP19A1TBXAS1PRKCI | |
| SCHEMBL11006560 | 0.72 | POLB (0.52) | KMT2AMEN1CYP19A1TBXAS1PRKCI | |
| SCHEMBL30674929 | 0.72 | CYP11B1 (0.58) | KMT2AMEN1CYP19A1TBXAS1PRKCI | |
| SCHEMBL6987181 | 0.72 | CYP11B1 (0.72) | KMT2AMEN1CYP19A1TBXAS1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528195-A | Imidazole derivatives and salts thereof, their synthesis and intermediates and pharmaceutical formulations | THOROGOOD PETER B (GB) | 1985-07-09 | — | — | US | disclosed |
| EP-0003560-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-02 | — | — | EP | disclosed |
| US-4416895-A | ANTICOAGULANTS, ANTISHOCK AGENTS | BURROUGHS WELLCOME CO. (US) | 1983-11-22 | — | — | US | disclosed |