Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11014045 | 0.87 | DRD2 (0.40) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL11005867 | 0.86 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL11015653 | 0.86 | DRD1 (0.39) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL11008872 | 0.86 | DRD1 (0.39) | SLC6A2SLC6A4CYP3A4CYP2D6DRD1 | |
| SCHEMBL11014467 | 0.83 | BCHE (0.44) | — | |
| SCHEMBL11010302 | 0.82 | DRD1 (0.48) | CYP2D6DRD1DRD2PNPLA2HTR2A | |
| SCHEMBL11011835 | 0.81 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL11009453 | 0.78 | HTR2A (0.43) | CYP3A4CYP2D6DRD1DRD2PNPLA2 | |
| Hydrochloric Acid SCHEMBL11006734 | 0.77 | HTR2A (0.42) | CYP3A4CYP2D6DRD1DRD2PNPLA2 | |
| Bromide SCHEMBL11010072 | 0.75 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3DRD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4522946-A | FREE OF EXTRA-PYRAMIDAL SIDE EFFECTS | AYERST, MCKENNA & HARRISON, INC. (CA) | 1985-06-11 | — | — | US | disclosed |