Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1099297 | 0.86 | CA1 (0.44) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL1108523 | 0.86 | CA1 (0.44) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL10067736 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ACA2CYP19A1 | |
| SCHEMBL27540875 | 0.82 | GBA1 (0.51) | ALDH1A1PKMSMN1; SMN2LMNA | |
| SCHEMBL1108530 | 0.78 | CXCR4 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL1099551 | 0.78 | CXCR4 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL1100869 | 0.77 | MMP1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL1108518 | 0.77 | MMP1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL1100132 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2APKMCA1 | |
| SCHEMBL7135320 | 0.76 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153673-B2 | Metalloproteinase inhibitors | ASTRAZENECA AB (SE) | 2012-04-10 | — | — | US | disclosed |