Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | TTR | P02766 | 1/20 | 0.63 |
| ▸ | PPOX | P50336 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.47 |
| ▸ | LIPE | Q05469 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10846284 | 0.86 | MAPT (0.68) | RAB9AMAPTNPSR1POLBLMNA | |
| SCHEMBL11008594 | 0.84 | RAB9A (0.54) | RAB9AMEN1TTRPPOXKMT2A | |
| SCHEMBL11147168 | 0.84 | MEN1 (0.72) | RAB9AMEN1TTRPPOXKMT2A | |
| SCHEMBL9768812 | 0.84 | MEN1 (0.72) | RAB9AMEN1TTRPPOXKMT2A | |
| SCHEMBL11108780 | 0.84 | RAB9A (0.53) | RAB9AMEN1TTRPPOXKMT2A | |
| SCHEMBL11015705 | 0.82 | MAPT (0.64) | RAB9AMAPTNPSR1POLBLMNA | |
| Acifluorfen SCHEMBL7586484 | 0.82 | MEN1 (0.68) | RAB9AMEN1TTRPPOXKMT2A | |
| SCHEMBL10773705 | 0.82 | RAB9A (0.52) | RAB9AMEN1TTRPPOXKMT2A | |
| SCHEMBL10772934 | 0.82 | RAB9A (0.52) | RAB9AMEN1TTRPPOXKMT2A | |
| SCHEMBL10452504 | 0.81 | KMT2A (0.69) | RAB9AMEN1TTRPPOXKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556413-A | POSTEMERGENCE AND PREEMERGENCE HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1985-12-03 | — | — | US | disclosed |
| EP-0109575-A2 | Benzoic-acid derivatives, process and means for its production | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-05-30 | — | — | EP | disclosed |