Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 2/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11010472 | 1.00 | MAOA (0.43) | MAOAMAOBHRH3CCR3CYP2C9 | |
| SCHEMBL11010469 | 1.00 | MAOA (0.43) | MAOAMAOBHRH3CCR3CYP2C9 | |
| SCHEMBL11008268 | 0.90 | HRH3 (0.41) | HRH3CCR3KCNH2ALDH1A1LMNA | |
| SCHEMBL11008266 | 0.90 | HRH3 (0.41) | HRH3CCR3KCNH2ALDH1A1LMNA | |
| SCHEMBL11008261 | 0.90 | HRH3 (0.41) | HRH3CCR3KCNH2ALDH1A1LMNA | |
| SCHEMBL11009335 | 0.87 | MAOA (0.44) | MAOAMAOBCCR3LPLLIPG | |
| SCHEMBL11009339 | 0.87 | MAOA (0.44) | MAOAMAOBCCR3LPLLIPG | |
| SCHEMBL11009329 | 0.85 | OPRM1 (0.40) | — | |
| SCHEMBL11009327 | 0.85 | OPRM1 (0.40) | — | |
| SCHEMBL11009325 | 0.85 | OPRM1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131837-A1 | Liquid crystalline compounds | MERCK PATENT GmbH (DE) | 1985-01-23 | — | — | EP | disclosed |