Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | VDR | P11473 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13953779 | 0.92 | CNR1 (0.50) | CNR1CNR2BACE1VDRALOX5 | |
| SCHEMBL11720734 | 0.90 | CNR1 (0.48) | CNR1CNR2BACE1VDRALOX5 | |
| SCHEMBL9734907 | 0.87 | CNR1 (0.48) | CNR1CNR2BACE1ALOX5GPR84 | |
| SCHEMBL22490117 | 0.85 | EGFR (0.46) | BACE1VDRCA2 | |
| SCHEMBL606251 | 0.85 | TRPA1 (0.46) | BACE1LPLLIPGL3MBTL1 | |
| SCHEMBL28635844 | 0.85 | TYR (0.50) | CNR1CNR2VDRALOX5LPL | |
| SCHEMBL14922851 | 0.84 | BACE1 (0.42) | CNR1CNR2BACE1VDRALOX5 | |
| SCHEMBL6756665 | 0.83 | VDR (0.47) | CNR1CNR2VDRALOX5LPL | |
| SCHEMBL18007124 | 0.82 | CNR1 (0.48) | CNR1CNR2BACE1VDRALOX5 | |
| SCHEMBL11010600 | 0.82 | CNR1 (0.44) | CNR1CNR2BACE1ALOX5GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537720-A | N-substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamino)-4-oxo-azetidines and process | ELI LILLY AND COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| US-4477660-A | 7-(S)-Acylaminocephalosporin sulfones and process | ELI LILLY AND COMPANY (US) | 1984-10-16 | — | — | US | disclosed |
| US-4474879-A | Process for 3-hydroxymethyl cephalosporin sulfones | ELI LILLY AND COMPANY (US) | 1984-10-02 | — | — | US | disclosed |
| US-4459405-A | Desacetylcephalosporin sulfones | ELI LILLY AND COMPANY (US) | 1984-07-10 | — | — | US | disclosed |
| EP-0109301-A2 | 7-(S)-acylaminocephalosporin sulfones and process | ELI LILLY AND COMPANY (US) | 1984-05-23 | — | — | EP | disclosed |
| EP-0109300-A2 | Desacetylcephalosporin sulfones | ELI LILLY AND COMPANY (US) | 1984-05-23 | — | — | EP | disclosed |
| US-4436596-A | N-Substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamido)-4-oxo-azetidines and process | ELI LILLY AND COMPANY (US) | 1984-03-13 | — | — | US | disclosed |