Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.81 |
| ▸ | PARP1 | P09874 | 7/20 | 0.69 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.69 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.69 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.69 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.69 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NMT1 | P30419 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11011741 | 1.00 | CREBBP (0.81) | CREBBPPARP1PARP10PARP14PARP15 | |
| SCHEMBL17395887 | 0.89 | CREBBP (1.00) | CREBBPPARP1PARP10PARP14PARP15 | |
| SCHEMBL17395885 | 0.89 | CREBBP (1.00) | CREBBPPARP1PARP10PARP14PARP15 | |
| SCHEMBL9364423 | 0.84 | CREBBP (0.79) | CREBBPPARP1PARP10PARP14PARP15 | |
| SCHEMBL15798246 | 0.84 | CREBBP (0.79) | CREBBPPARP1PARP10PARP14PARP15 | |
| SCHEMBL9364431 | 0.84 | CREBBP (0.79) | CREBBPPARP1PARP10PARP14PARP15 | |
| SCHEMBL1552033 | 0.82 | LPAR2 (1.00) | CREBBPPARP1PARP10PARP14PARP15 | |
| SCHEMBL441804 | 0.82 | LPAR2 (1.00) | CREBBPPARP1PARP10PARP14PARP15 | |
| SCHEMBL441805 | 0.82 | LPAR2 (1.00) | CREBBPPARP1PARP10PARP14PARP15 | |
| SCHEMBL11012619 | 0.81 | NMT1 (0.70) | CREBBPLPAR1LPAR2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500719-A | Process for the preparation of N-alkenylphenylmaleimides and N,N'-[alkenylenephenylene]bismalemides | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1985-02-19 | — | — | US | disclosed |
| US-4376206-A | QUICK-CURABLE HEAT RESISTANT RESINS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1983-03-08 | — | — | US | disclosed |