SCHEMBL1101181

SCHEMBL1101181

CCCCCC=COC=CCCCCC

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.48
TRPV1 Q8NER1 2/20 0.48
TSHR P16473 3/20 0.44
ALDH1A1 P00352 1/20 0.44
LPAR3 Q9UBY5 1/20 0.42
GMNN O75496 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX15 P16050 1/20 0.41
APEX1 P27695 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4442060 1.00 FAAH (0.48) FAAHTRPV1TSHRALDH1A1LPAR3
SCHEMBL9785130 0.97 FAAH (0.52) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL9785182 0.97 FAAH (0.52) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL2057348 0.97 FAAH (0.52) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL9785139 0.97 FAAH (0.52) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL77403 0.97 FAAH (0.52) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL1974873 0.97 FAAH (0.52) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL9785179 0.97 FAAH (0.52) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL1974180 0.97 FAAH (0.52) FAAHTRPV1TSHRGMNNUSP2
SCHEMBL809572 0.97 FAAH (0.52) FAAHTRPV1TSHRGMNNUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10286377-B1 Electrode array device having an adsorbed porous reaction layer CUSTOMARRAY, INC. (US) 2019-05-14 US claimed
US-9339782-B1 Electrode array device having an adsorbed porous reaction layer CUSTOMARRAY, INC. (US) 2016-05-17 US claimed
CN-101473220-B Electrode array device having an adsorbed porous reaction layer COMBIMATRIX CORP 2012-11-28 CN claimed
CN-101156062-B Electrode array device having an adsorbed porous reaction layer having a linker moiety COMBIMATRIX CORP. (US) 2012-02-22 CN claimed
US-7541314-B2 Microarray having a base cleavable sulfonyl linker COMBIMATRIX CORPORATION (US) 2009-06-02 US claimed
EP-1945750-A2 MICROARRAY HAVING A BASE CLEAVABLE SUCINATE LINKER Combimatrix Corporation (US) 2008-07-23 EP claimed
US-20080125327-A1 Bonding amino moieties to solid surface with reactive hydroxyl groups, bonding succinate moieties to the amine groups through amide bonds to form cleavable linkers attached to the solid surface, bonding a succinate group, a sugar group and a base group, synthesizing oligonucleotides CUSTOMARRAY, INC. 2008-05-29 US claimed
US-20080105541-A1 Electrode Array Device Having An Adsorbed Porous Reaction Layer STRATHMANN MICHAEL P 2008-05-08 US claimed
WO-2007100793-A2 MICROARRAY HAVING A BASE CLEAVABLE SULFONYL LINKER COMBIMATRIX CORPORATION (US) 2007-09-07 WO claimed
US-20070202509-A1 Microarray having a base cleavable sulfonyl linker COMBIMATRIX CORPORATION 2007-08-30 US claimed
EP-1812190-A2 ELECTRODE ARRAY DEVICE HAVING AN ADSORBED POROUS REACTION LAYER Combimatrix Corporation (US) 2007-08-01 EP claimed
WO-2007035500-A2 MICROARRAY HAVING A BASE CLEAVABLE SUCCINATE LINKER COMBIMATRIX CORPORATION (US) 2007-03-29 WO claimed
US-20070065877-A1 Microarray having a base cleavable succinate linker COMBIMATRIX CORPORATION 2007-03-22 US claimed
WO-2006055943-A2 ELECTRODE ARRAY DEVICE HAVING AN ADSORBED POROUS REACTION LAYER HAVING A LINKER MOIETY COMBIMATRIX CORPORATION (US) 2006-05-26 WO claimed
WO-2006055810-A2 ELECTRODE ARRAY DEVICE HAVING AN ADSORBED POROUS REACTION LAYER COMBIMATRIX CORPORATION (US) 2006-05-26 WO claimed
US-20060105355-A1 Electrode array device having an adsorbed porous reaction layer having a linker moiety KARL MAURER 2006-05-18 US claimed
US-20060102471-A1 Electrode array device having an adsorbed porous reaction layer CUSTOMARRAY, INC. 2006-05-18 US claimed
US-5324616-A Encapsulated toner compositions and processes thereof XEROX CORPORATION (US) 1994-06-28 US claimed
US-5045428-A Encapsulated toner compositions and processes thereof XEROX CORPORATION (US) 1991-09-03 US claimed
EP-0148632-A2 Ionomers with improved low temperature flex-crack resistance and improved process economics E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-07-17 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070202509-A1 Microarray having a base cleavable sulfonyl linker DPP8, DPP4, SI FAAH 2497/4885TRPV1 3467/4885TSHR 1870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.