Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10434662 | 0.81 | MAPT (0.43) | MAPTKMT2AKDM4EMEN1THRB | |
| SCHEMBL27624585 | 0.80 | ALDH1A1 (0.40) | MAPTKMT2AKDM4EMEN1THRB | |
| SCHEMBL796531 | 0.79 | KMT2A (0.48) | MAPTKMT2AKDM4EMEN1THRB | |
| SCHEMBL8995877 | 0.77 | GAA (0.47) | MAPTKMT2AMEN1GAATDP1 | |
| SCHEMBL5618066 | 0.76 | MAPT (0.46) | MAPTKMT2AKDM4EMEN1THRB | |
| SCHEMBL11106668 | 0.76 | MAPT (0.46) | MAPTKMT2AKDM4EMEN1THRB | |
| SCHEMBL10898590 | 0.76 | MAPT (0.42) | MAPTKMT2AKDM4EMEN1THRB | |
| SCHEMBL11720410 | 0.75 | MAPT (0.59) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL20862099 | 0.75 | MAPT (0.40) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL29411918 | 0.75 | RAB9A (0.45) | MAPTKMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135017-A1 | Process for the stabilisation of poly(phenylene ether) solutions | BASF Aktiengesellschaft (DE) | 1985-03-27 | — | — | EP | disclosed |
| EP-0072621-A1 | Alkyleneoxy compounds, their preparation and their use as fugitive tints | MILLIKEN RESEARCH CORPORATION (US) | 1983-02-23 | — | — | EP | disclosed |