Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22775248 | 0.83 | CA12 (0.48) | TSHRALDH1A1MAPK1HPGDHSD17B10 | |
| SCHEMBL20444303 | 0.81 | ALDH1A1 (0.50) | CYP3A4TSHRALDH1A1MAPK1POLB | |
| SCHEMBL2014424 | 0.80 | TSHR (0.52) | TSHRHPGDHSD17B10GAANPFFR2 | |
| SCHEMBL31599679 | 0.80 | TSHR (0.52) | TSHRHPGDHSD17B10GAANPFFR2 | |
| SCHEMBL11694880 | 0.80 | TDP1 (0.42) | CYP3A4TSHRALDH1A1MAPK1THRB | |
| SCHEMBL32680308 | 0.80 | TDP1 (0.42) | CYP3A4TSHRALDH1A1MAPK1THRB | |
| SCHEMBL8246414 | 0.79 | ALDH1A1 (0.53) | CYP3A4TSHRALDH1A1MAPK1POLB | |
| SCHEMBL31118863 | 0.79 | ALDH1A1 (0.53) | CYP3A4TSHRALDH1A1MAPK1POLB | |
| SCHEMBL9274485 | 0.77 | MEN1 (0.38) | TSHRHPGDCASP1NPFFR2MEN1 | |
| SCHEMBL11010663 | 0.77 | TDP1 (0.48) | CYP3A4TSHRALDH1A1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500719-A | Process for the preparation of N-alkenylphenylmaleimides and N,N'-[alkenylenephenylene]bismalemides | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1985-02-19 | — | — | US | disclosed |
| US-4376206-A | QUICK-CURABLE HEAT RESISTANT RESINS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1983-03-08 | — | — | US | disclosed |