Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31599679 | 1.00 | TSHR (0.52) | TSHRNPFFR2SRD5A2MEN1KMT2A | |
| SCHEMBL10336410 | 0.82 | HSD17B10 (0.48) | TSHRNPFFR2GAAHSD17B10HPGD | |
| SCHEMBL30482512 | 0.82 | MEN1 (0.38) | TSHRNPFFR2SRD5A2MEN1KMT2A | |
| SCHEMBL19153456 | 0.82 | TSHR (0.45) | TSHRNPFFR2KMT2ASMN1; SMN2GAA | |
| SCHEMBL11145835 | 0.82 | HSP90AA1 (0.49) | TSHRNPFFR2SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL9274485 | 0.82 | MEN1 (0.38) | TSHRNPFFR2SRD5A2MEN1KMT2A | |
| SCHEMBL6128400 | 0.82 | CYP3A4 (0.45) | MEN1KMT2AGAAKDM4ENPC1 | |
| SCHEMBL11012802 | 0.80 | CYP3A4 (0.46) | TSHRNPFFR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22775248 | 0.80 | CA12 (0.48) | TSHRNPFFR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7982038 | 0.80 | MAOA (0.43) | TSHRMEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12404253-B2 | 2,4,6-trisubstituted 1,3,5-triazines as modulators of CX3CR1 | ASTRAZENECA AB (SE) | 2025-09-02 | — | — | US | disclosed |
| EP-4605388-A1 | <SUP2/>? <SUB2/>?3?2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CXCR1 | Astrazeneca AB (SE) | 2025-08-27 | — | — | EP | disclosed |
| US-20240383866-A1 | 2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CX3CR1 | ASTRAZENECA AB (SE) | 2024-11-21 | — | — | US | disclosed |
| US-20240199558-A1 | 2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CX3CR1 | ASTRAZENECA AB (SE) | 2024-06-20 | — | — | US | disclosed |
| WO-2024083933-A1 | 2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CX 3CR1 | ASTRAZENECA AB (SE) | 2024-04-25 | — | — | WO | disclosed |
| US-20220179312-A1 | PATTERN FORMING METHOD AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE | FUJIFILM CORPORATION (JP) | 2022-06-09 | — | — | US | disclosed |
| US-9417530-B2 | Method for developing resist, method for forming a resist pattern, method for producing a mold, and developing fluid utilized in these methods | FUJIFILM CORPORATION (JP) | 2016-08-16 | — | — | US | disclosed |
| US-20150008211-A1 | METHOD FOR DEVELOPING RESIST, METHOD FOR FORMING A RESIST PATTERN, METHOD FOR PRODUCING A MOLD, AND DEVELOPING FLUID UTILIZED IN THESE METHODS | FUJIFILM CORPORATION (JP) | 2015-01-08 | — | — | US | disclosed |
| CN-102652159-B | Stain-resistant aqueous coating composition | AKZO NOBEL COATINGS INT BV | 2014-08-13 | — | — | CN | disclosed |
| EP-2513237-B1 | STAIN-BLOCKING AQUEOUS COATING COMPOSITION | AKZO NOBEL COATINGS INT BV (NL) | 2014-06-18 | — | — | EP | disclosed |
| WO-2011073164-A1 | STAIN-BLOCKING AQUEOUS COATING COMPOSITION | AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) | 2011-06-23 | — | — | WO | disclosed |
| EP-0121192-B1 | ANALYTICAL TEST COMPOSITION, DEVICE, METHOD FOR ITS PREPARATION AND METHOD FOR THE DETERMINATION OF PEROXIDATIVELY ACTIVE SUBSTANCE | MILES INC. (US) | 1990-06-27 | — | — | EP | disclosed |
| EP-0310061-A1 | 5-Mono or Disubstituted-3-(phenyl or 2-naphthalenyl)-3-[(1H-imidazol-1-ylmethyl) or (1H-1,2,4-triazol-1-ylmethyl)]-2-(methyl or benzyl)isoxazolidines | FISONS CORPORATION (US) | 1989-04-05 | — | — | EP | disclosed |
| US-4785117-A | 5,5-disubstituted-3-phenyl-3-phenyl-3-[(1H-imidazol-1-ylmethyl) or (1H-1,2,4-triazol-1-ylmethyl)]-2-methylisoxazolidine derivatives (IR 3012) | PENNWALT CORPORATION (US) | 1988-11-15 | — | — | US | disclosed |
| US-4650910-A | CLEAVAGE OF N-ACYL-B-PHENETHYLAMINES WITH BASE | BAYER AKTIENGESELLSCHAFT (DE) | 1987-03-17 | — | — | US | disclosed |
| EP-0197274-A1 | Process for the preparation of substituted styrenes | BAYER AG (DE) | 1986-10-15 | — | — | EP | disclosed |
| EP-0121192-A2 | Analytical test composition, device, method for its preparation and method for the determination of peroxidatively active substance | MILES INC. (US) | 1984-10-10 | — | — | EP | disclosed |
| US-4447542-A | USING SUBSTITUTED CUMENE HYDROPEROXIDE AND INDICATOR; COLORIMETRIC ANALYSIS | MILES LABORATORIES, INC. (US) | 1984-05-08 | — | — | US | disclosed |
| US-4085165-A | ISOCYANATE PREPOLYMER, VINYL COMPOUND, POLYAMINE OR POLYETHER CURING AGENT | BRIDGESTONE TIRE CO., LTD. (JA) | 1978-04-18 | — | — | US | disclosed |
| US-4016341-A | REDUCING SCALE DEPOSITS BY COATING SURFACES WITH PHOSPHORIC ESTERS OR SALTS | SHIN-ETSU CHEMICAL COMPANY LIMITED (JA) | 1977-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199558-A1 | 2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CX3CR1 | CX3CR1, CCR2, CCR5 | TSHR 1113/4885NPFFR2 848/4885SRD5A2 1896/4885 |
| US-20240383866-A1 | 2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CX3CR1 | CX3CR1, CCR2, CCR5 | TSHR 1113/4885NPFFR2 848/4885SRD5A2 1896/4885 |
| US-12404253-B2 | 2,4,6-trisubstituted 1,3,5-triazines as modulators of CX3CR1 | CX3CR1, CCR2, CCR5 | TSHR 1113/4885NPFFR2 848/4885SRD5A2 1896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.