Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.33 |
| ▸ | PNPO | Q9NVS9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11014182 | 0.81 | PNPO (0.36) | PNPOCYP1A2CYP2D6CYP2C19HIF1A | |
| SCHEMBL11239732 | 0.81 | CYP1A2 (0.33) | PNPOCYP1A2CYP2D6CYP2C19HIF1A | |
| Hydrochloric Acid SCHEMBL11016843 | 0.78 | KDM4E (0.37) | PNPOCYP1A2CYP2D6CYP2C19HIF1A | |
| SCHEMBL11014309 | 0.75 | KDM4E (0.35) | PNPOCYP1A2CYP2D6CYP2C19HIF1A | |
| SCHEMBL11010754 | 0.74 | PTGS2 (0.38) | CYP1A2CYP2D6CYP2C19HIF1AALDH1A1 | |
| SCHEMBL11013064 | 0.74 | KDM4E (0.34) | PNPOCYP1A2CYP2D6CYP2C19HIF1A | |
| SCHEMBL11736194 | 0.73 | KDM4E (0.42) | PNPOCYP1A2CYP2D6CYP2C19HIF1A | |
| Hydrochloric Acid SCHEMBL11013110 | 0.73 | PNPO (0.33) | PNPOCYP1A2CYP2D6CYP2C19HIF1A | |
| SCHEMBL11244339 | 0.71 | LMNA (0.41) | PNPOCYP1A2CYP2D6CYP2C19HIF1A | |
| SCHEMBL11736210 | 0.71 | KDM4E (0.40) | PNPOCYP1A2CYP2D6CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4546106-A | ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1985-10-08 | — | — | US | disclosed |