Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.57 |
| ▸ | CA1 | P00915 | 4/20 | 0.57 |
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | CA6 | P23280 | 4/20 | 0.57 |
| ▸ | CA7 | P43166 | 4/20 | 0.57 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM6B | O15054 | 4/20 | 0.49 |
| ▸ | KDM4A | O75164 | 4/20 | 0.49 |
| ▸ | KDM4D | Q6B0I6 | 4/20 | 0.49 |
| ▸ | KDM3B | Q7LBC6 | 4/20 | 0.49 |
| ▸ | HIF1AN | Q9NWT6 | 4/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3160169 | 0.83 | KDM6B (0.63) | CA12CA1CA2CA6CA7 | |
| SCHEMBL10766398 | 0.82 | KDM4E (0.55) | CA12CA1CA2CA6CA7 | |
| SCHEMBL15349519 | 0.81 | KDM6B (0.60) | CA12CA1CA2CA6CA7 | |
| SCHEMBL1014580 | 0.80 | KDM4E (0.58) | CA12CA1CA2CA6CA7 | |
| SCHEMBL3583829 | 0.78 | KDM6B (0.55) | CA12CA1CA2CA6CA7 | |
| SCHEMBL2898616 | 0.78 | GAA (0.56) | CA12CA1CA2CA6CA7 | |
| SCHEMBL2902593 | 0.77 | ALDH1A1 (0.66) | CA12CA1CA2CA6CA7 | |
| SCHEMBL9781009 | 0.77 | ALDH1A1 (0.54) | CA12CA1CA2CA6CA7 | |
| SCHEMBL3824059 | 0.76 | GAA (0.54) | CA12CA1CA2CA6CA7 | |
| SCHEMBL13724398 | 0.76 | ALDH1A1 (0.54) | CA12CA1CA2CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142040-A2 | Substituted pyrimidines | BAYER AG (DE) | 1985-05-22 | — | — | EP | disclosed |