Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.48 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843371 | 0.87 | CHRM2 (0.69) | MEN1KMT2AATMCHRM2POLB | |
| SCHEMBL22305089 | 0.86 | KMT2A (0.68) | MEN1KMT2AATMCHRM2POLB | |
| Methane SCHEMBL28948442 | 0.85 | CHRM2 (0.67) | MEN1KMT2AATMCHRM2POLB | |
| SCHEMBL8497081 | 0.85 | MEN1 (0.62) | MEN1KMT2AATMCHRM2POLB | |
| SCHEMBL3425734 | 0.84 | BCHE (0.71) | MEN1KMT2AATMALDH1A1 | |
| SCHEMBL16523598 | 0.83 | KMT2A (0.70) | MEN1KMT2AATMCHRM2POLB | |
| SCHEMBL29802812 | 0.83 | CA12 (0.64) | MEN1KMT2AATMCHRM2MAPT | |
| SCHEMBL16523593 | 0.83 | KMT2A (0.70) | MEN1KMT2AATMCHRM2POLB | |
| SCHEMBL31547203 | 0.83 | MEN1 (0.70) | MEN1KMT2AATMCHRM2POLB | |
| SCHEMBL9483777 | 0.83 | MAPT (0.58) | MEN1KMT2AATMCHRM2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122011028-A | Method for efficiently preparing various substituted chiral phosphoramides | 上海交通大学 | 2026-05-12 | — | — | CN | claimed |
| CN-119350180-A | Industrial preparation method and application of high-purity alpha-aminonitrile | 哈尔滨理工大学 | 2025-01-24 | — | — | CN | claimed |
| JP-57028011-A | — | — | None | — | — | JP | disclosed |
| CN-122011028-A | Method for efficiently preparing various substituted chiral phosphoramides | 上海交通大学 | 2026-05-12 | — | — | CN | disclosed |
| WO-2025264680-A1 | ANTICANCER POLYHETEROCYCLIC COMPOUNDS AND ASSOCIATED METHODS | UNIVERSITY OF DENVER (US) | 2025-12-26 | — | — | WO | disclosed |
| US-20250382302-A1 | Anticancer polyheterocyclic compounds and associated methods | UNIV OF DENVER (US) | 2025-12-18 | — | — | US | disclosed |
| CN-119350180-A | Industrial preparation method and application of high-purity alpha-aminonitrile | 哈尔滨理工大学 | 2025-01-24 | — | — | CN | disclosed |
| US-11773064-B2 | 4-carboxamido-isoindolinone derivatives as selective PARP-1 inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2023-10-03 | — | — | US | disclosed |
| CN-110818576-B | Secondary amine derivative synthesized by rare earth catalysis and preparation method thereof | 温州大学 | 2023-02-24 | — | — | CN | disclosed |
| US-20220363636-A1 | 4-CARBOXAMIDO-ISOINDOLINONE DERIVATIVES AS SELECTIVE PARP-1 INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2022-11-17 | — | — | US | disclosed |
| US-11420940-B2 | 4-carboxamido-isoindolinone derivatives as selective parp-1 inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2022-08-23 | — | — | US | disclosed |
| US-7235664-B2 | Anthranilamides with heteroarylsulfonyl side chain, process of preparation, and use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-06-26 | — | — | US | disclosed |
| US-7235664-B2 | Anthranilamides with heteroarylsulfonyl side chain, process of preparation, and use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-06-26 | — | — | US | disclosed |
| US-20070117807-A1 | ANTHRANILAMIDES AND METHODS OF THEIR USE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-05-24 | — | — | US | disclosed |
| US-20070117807-A1 | ANTHRANILAMIDES AND METHODS OF THEIR USE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-05-24 | — | — | US | disclosed |
| WO-2007009976-A1 | POLYMERISATION CATALYST SYSTEM BASED ON MONOOXIME LIGANDS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-01-25 | — | — | WO | disclosed |
| EP-1746112-A1 | Polymerisation catalyst system based on monooxime ligands | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-01-24 | — | — | EP | disclosed |
| US-4508723-A | 6-Azaoligocycloalkylmethyleneaminopenam compounds | CIBA GEIGY CORPORATION (US) | 1985-04-02 | — | — | US | disclosed |
| JP-S5728011-A | PREPARATION OF AMINE USING SELENOPHENOL | WAKO PURE CHEM IND LTD | 1982-02-15 | — | — | JP | disclosed |
| EP-0005014-A1 | Clavulanic acid derivatives, preparation and compositions | BEECHAM GROUP PLC (GB) | 1979-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773064-B2 | 4-carboxamido-isoindolinone derivatives as selective PARP-1 inhibitors | PARP1, PARP2, PARP12 | MEN1 4521/4885KMT2A 1211/4885ATM 104/4885 |
| US-11420940-B2 | 4-carboxamido-isoindolinone derivatives as selective parp-1 inhibitors | PARP1, PARP2, PARP11 | MEN1 4483/4885KMT2A 1614/4885ATM 160/4885 |
| US-20220363636-A1 | 4-CARBOXAMIDO-ISOINDOLINONE DERIVATIVES AS SELECTIVE PARP-1 INHIBITORS | PARP1, PARP2, PARP12 | MEN1 4541/4885KMT2A 1196/4885ATM 102/4885 |
| US-20250382302-A1 | Anticancer polyheterocyclic compounds and associated methods | HCCS, POLI, PARP1 | MEN1 2192/4885KMT2A 2163/4885ATM 1873/4885 |
| US-20070117807-A1 | ANTHRANILAMIDES AND METHODS OF THEIR USE | KCNH1, KCNH2, KCNJ2 | MEN1 3308/4885KMT2A 587/4885ATM 2684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.