SCHEMBL843371

SCHEMBL843371

c1coc(CNCc2ccco2)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.69
KMT2A Q03164 3/20 0.68
MEN1 O00255 2/20 0.68
POLB P06746 1/20 0.66
ATM Q13315 1/20 0.56
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
TSHR P16473 1/20 0.53
GAA P10253 2/20 0.53
USP2 O75604 1/20 0.52
EPHX2 P34913 2/20 0.50
ALDH1A1 P00352 1/20 0.50
KDM4A O75164 1/20 0.49
KDM4B O94953 1/20 0.49
KDM5C P41229 1/20 0.49
KDM5B Q9UGL1 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA4 P22748 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL28948442 0.97 CHRM2 (0.67) CHRM2KMT2AMEN1POLBATM
SCHEMBL1642902 0.90 CHRM2 (0.77) CHRM2KMT2AMEN1POLBATM
SCHEMBL22305089 0.89 KMT2A (0.68) CHRM2KMT2AMEN1POLBATM
SCHEMBL4506591 0.88
SCHEMBL11014192 0.87 MEN1 (0.71) CHRM2KMT2AMEN1POLBATM
SCHEMBL2718733 0.86
SCHEMBL13278276 0.86 CHRM2 (0.85) CHRM2KMT2AMEN1POLBATM
SCHEMBL14040527 0.86
SCHEMBL30141723 0.86 CHRM2 (0.92) CHRM2KMT2AMEN1POLBATM
SCHEMBL11069595 0.84 CHRM2 (0.96) CHRM2KMT2AMEN1POLBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112979919-A Preparation method of bio-based self-repairing polyurethane elastomer 中国林业科学研究院林产化学工业研究所 2021-06-18 CN claimed
US-7615659-B2 Preparing a palladium(0) compound by the reaction of a palladium compound with a silicone containing compound in the presence of a base; palladium(0) compounds are suitable as homogeneous catalysts, or as precursors for preparing homogeneous catalysts; storage stability UMICORE AG & CO. KG (DE) 2009-11-10 US claimed
EP-1784180-A4 2-AMINO 1H IMIDAZO RING SYSTEMS AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2009-07-22 EP claimed
EP-1558621-B1 METHODS FOR THE PREPARATION OF COMPOUNDS CONTAINING PALLADIUM (0) UMICORE AG & CO KG (DE) 2008-01-23 EP claimed
EP-1784180-A2 2-AMINO 1H IMIDAZO RING SYSTEMS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-05-16 EP claimed
US-20060106239-A1 Method for the production of compounds containing palladium(0) UMICORE AG & CO. KG (DE) 2006-05-18 US claimed
WO-2006029115-A2 2-AMINO 1H IMIDAZO RING SYSTEMS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-03-16 WO claimed
CN-1720253-A Method for the production of compounds containing palladium (0) UMICORE AG & CO KG (DE) 2006-01-11 CN claimed
US-6686495-B2 IN PRESENCE OF PALLADIUM CATALYST; USEFUL IN PRODUCING CHEMICAL INTERMEDIATES FOR PHARMACEUTICALS, OPTICAL BRIGHTENING AGENTS AND AGROCHEMICALS OMG AG & CO KG (DE) 2004-02-03 US claimed
US-20020107426-A1 Process for the preparation of mono-, bi- or poly- functional biaryls UMICORE AG & CO. KG (DE) 2002-08-08 US claimed
EP-1199292-A1 Process for the production of mono-, bi- or polyfunctional biaryls OMG AG & Co. KG (DE) 2002-04-24 EP claimed
US-4192820-A Preparation of 3-methyl-2-buten-1-al BASF AKTIENGESELLSCHAFT (DE) 1980-03-11 US claimed
US-12528948-B2 Amino (meth)acrylates ALLNEX BELGIUM S.A. (BE) 2026-01-20 US disclosed
US-20260015458-A1 POLYCARBONATE RESIN COMPOSITION MITSUBISHI CHEMICAL CORPORATION (JP) 2026-01-15 US disclosed
CN-119186628-A Catalyst for reductive amination of aldehyde ketone compounds, preparation method and application 天津大学 2024-12-27 CN disclosed
WO-2024204727-A1 POLYCARBONATE RESIN COMPOSITION 三菱ケミカル株式会社 2024-10-03 WO disclosed
US-4165342-A BY OXIDATIVE DEHYDROGENATION OF THE ALCOHOL, LAYERS OF SILVER AND COPPER CATALYST CRYSTALS BASF AKTIENGESELLSCHAFT (DE) 1979-08-21 US disclosed
US-3992428-A REACTING UREA AND HEXAMETHYLDISILAZANE IN THE PRESENCE OF A NITROGEN CONTAINING SALT WACKER-CHEMIE GMBH (DT) 1976-11-16 US disclosed
US-3975363-A Poly(diels-alder) polymer TRW INC. (US) 1976-08-17 US disclosed
US-3967091-A Capillary flow weld-bonding THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060106239-A1 Method for the production of compounds containing palladium(0) RPS19, SCO2, MMS19 CHRM2 1373/4885KMT2A 2029/4885MEN1 529/4885
US-20260015458-A1 POLYCARBONATE RESIN COMPOSITION CAD, DCTN3, DCTN1 CHRM2 4772/4885KMT2A 3639/4885MEN1 4018/4885
US-12528948-B2 Amino (meth)acrylates MAT2B, MAT1A, MMAB CHRM2 696/4885KMT2A 173/4885MEN1 14/4885
US-20020107426-A1 Process for the preparation of mono-, bi- or poly- functional biaryls CYP4F3, CYP4F2, CYP2F1 CHRM2 2161/4885KMT2A 2368/4885MEN1 1511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.