Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3395281 | 0.76 | ALDH1A1 (0.55) | KDM4EALDH1A1TSHRUSP2KMT2A | |
| SCHEMBL16807565 | 0.73 | ELANE (0.46) | KDM4ETSHRMAPK1HCRTR1HCRTR2 | |
| SCHEMBL17449213 | 0.72 | ALDH1A1 (0.44) | KDM4EALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL31278612 | 0.72 | ALDH1A1 (0.44) | KDM4EALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL2543684 | 0.71 | ALDH1A1 (0.45) | KDM4EALDH1A1TSHRUSP2KMT2A | |
| SCHEMBL9955618 | 0.70 | ALDH1A1 (0.57) | KDM4EALDH1A1TSHRUSP2KMT2A | |
| SCHEMBL29601706 | 0.69 | KDM4E (0.46) | KDM4EALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL5649730 | 0.69 | RAB9A (0.66) | KDM4EALDH1A1TSHRUSP2KMT2A | |
| SCHEMBL6902624 | 0.69 | KDM4E (0.46) | KDM4EALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL2487359 | 0.69 | ALDH1A1 (0.56) | KDM4EALDH1A1TSHRUSP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159640-A1 | 4-Methoxy-2,2'-bipyridyl-6-aldoximes, process and intermediates for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-10-30 | — | — | EP | disclosed |