Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11012143 | 0.99 | ACHE (0.51) | ACHEOPRM1CCR3OPRD1OPRK1 | |
| SCHEMBL10652466 | 0.88 | OPRM1 (0.55) | ACHEOPRM1CCR3OPRD1OPRK1 | |
| SCHEMBL11015643 | 0.88 | OPRM1 (0.61) | OPRM1OPRD1OPRK1ADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL10651492 | 0.87 | OPRM1 (0.54) | ACHEOPRM1OPRD1OPRK1ADRA1A | |
| Hydrochloric Acid SCHEMBL10656003 | 0.86 | OPRM1 (0.60) | OPRM1OPRD1OPRK1ADRA1AADRA1B | |
| SCHEMBL10656085 | 0.85 | OPRM1 (0.60) | OPRM1OPRD1OPRK1ADRA1AADRA1B | |
| SCHEMBL10653487 | 0.83 | OPRM1 (0.67) | OPRM1OPRD1OPRK1ADRA1AADRA1B | |
| SCHEMBL10653274 | 0.82 | OPRM1 (0.54) | OPRM1OPRD1OPRK1ADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL10655286 | 0.82 | OPRM1 (0.66) | OPRM1OPRD1OPRK1ADRA1AADRA1B | |
| SCHEMBL10656523 | 0.82 | OPRM1 (0.62) | OPRM1OPRD1OPRK1ADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4546105-A | ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-10-08 | — | — | US | claimed |