Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12767187 | 0.84 | LMNA (0.66) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4852673 | 0.83 | ATM (0.71) | LMNAL3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL3818640 | 0.81 | HDAC6 (0.66) | LMNAL3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL15106441 | 0.81 | TSHR (0.54) | LMNAL3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL22854680 | 0.80 | LMNA (0.55) | LMNAL3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL14363850 | 0.80 | KDM4E (0.60) | LMNAL3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL3714715 | 0.80 | SMN1; SMN2 (0.71) | LMNAL3MBTL1ALDH1A1KDM4EKMT2A | |
| SCHEMBL8242227 | 0.79 | NPC1 (0.70) | LMNAL3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL874882 | 0.78 | TSHR (0.58) | LMNAL3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL3821434 | 0.78 | TSHR (0.59) | LMNAL3MBTL1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4521420-A | Oxoquinazoline carbamates | BAYER AKTIENGESELLSCHAFT (DE) | 1985-06-04 | — | — | US | disclosed |
| EP-0101902-A1 | Oxoquinazoline-carbamic-acid ester | BAYER AG (DE) | 1984-03-07 | — | — | EP | disclosed |