Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 7/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12767187 | 0.96 | LMNA (0.66) | ATMSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL11014372 | 0.83 | LMNA (0.55) | ATMSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL28308015 | 0.83 | SMN1; SMN2 (1.00) | ATMSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL28308021 | 0.82 | LMNA (1.00) | ATMSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL28307048 | 0.82 | LMNA (1.00) | ATMSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL11501103 | 0.82 | PDE4A (0.70) | ATMSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL28453421 | 0.81 | LMNA (0.77) | ATMSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL5928664 | 0.78 | SMN1; SMN2 (0.92) | ATMSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL4958469 | 0.77 | LMNA (0.74) | ATMSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL4957089 | 0.76 | LMNA (1.00) | ATMSMN1; SMN2LMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008145830-A2 | NOVEL PRO-FLUORESCENT COMPOUNDS | QUIDD (FR) | 2008-12-04 | — | — | WO | claimed |
| WO-2008145830-A2 | NOVEL PRO-FLUORESCENT COMPOUNDS | QUIDD (FR) | 2008-12-04 | — | — | WO | disclosed |