Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148991 | 0.89 | CYP1A2 (0.48) | FAAHCYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL11011149 | 0.83 | FAAH (0.65) | FAAHRAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL1153371 | 0.79 | CYP1A2 (0.52) | FAAHCYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL29808949 | 0.79 | CYP1A2 (0.60) | CYP1A2CYP3A4CYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL11008711 | 0.79 | CYP1A2 (0.60) | CYP1A2CYP3A4CYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL8632798 | 0.79 | RAB9A (0.63) | CYP1A2CYP3A4CYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL10719163 | 0.77 | MRGPRX4 (0.57) | CYP1A2CYP3A4CYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL11262551 | 0.77 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL11267257 | 0.77 | SMN1; SMN2 (0.49) | FAAHCYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL10604932 | 0.76 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C19RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4546191-A | Trifluoromethyl-2-pyridinone or pyridinthione compounds and process for the preparation of the same | ISHIHARA SANGYO KAISHA LTD. (JP) | 1985-10-08 | — | — | US | disclosed |