Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.44 |
| ▸ | CCR5 | P51681 | 3/20 | 0.44 |
| ▸ | CCR8 | P51685 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12131376 | 0.80 | CCR1 (0.51) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL30567052 | 0.79 | KDM4E (0.50) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL7949955 | 0.78 | CCR1 (0.50) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL11004572 | 0.78 | FFAR1 (0.44) | CCR1CCR5CCR8FFAR1ALDH1A1 | |
| SCHEMBL11016110 | 0.76 | KDM4E (0.50) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL14263382 | 0.75 | CCR1 (0.58) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL10953652 | 0.75 | KDM4E (0.54) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL11030679 | 0.75 | KMT2A (0.37) | KDM4EPOLBTDP1MAPK1ALDH1A1 | |
| SCHEMBL15046246 | 0.74 | KDM4E (0.53) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL9356136 | 0.73 | KCNH2 (0.47) | KDM4ESMN1; SMN2L3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045277-B1 | VINYL-SUBSTITUTED 2,2'-BIPYRIDINES, POLYMERS PREPARED THEREFROM, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1985-10-02 | — | — | EP | disclosed |
| US-4424359-A | COMPLEX-FORMING POLYMERS, SCAVENGERS, VINYLATION | CIBA-GEIGY CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |
| EP-0045277-A2 | Vinyl-substituted 2,2'-bipyridines, polymers prepared therefrom, their preparation and their use | CIBA-GEIGY AG (CH) | 1982-02-03 | — | — | EP | disclosed |