SCHEMBL30567052

SCHEMBL30567052

OCCc1ccnc(-c2ccccn2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.50
LMNA P02545 3/20 0.50
CCR1 P32246 3/20 0.50
CCR5 P51681 3/20 0.50
CCR8 P51685 3/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
METAP1 P53582 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
KDM6B O15054 1/20 0.49
KDM4A O75164 1/20 0.49
KDM5C P41229 1/20 0.49
KDM4C Q9H3R0 1/20 0.49
KDM2A Q9Y2K7 1/20 0.49
KDM3A Q9Y4C1 1/20 0.49
TP53 P04637 3/20 0.44
TDP1 Q9NUW8 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4535559 0.85 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL29603676 0.85 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL27822958 0.82 ASIC3 (0.50) LMNAHIF1ATDP1NPC1RAB9A
Dipyridyl SCHEMBL8658875 0.81 CCR1 (0.46) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL10945468 0.81 KDM4E (0.48) KDM4ELMNACCR1CCR5CCR8
SCHEMBL17773804 0.80 KDM4E (0.55) KDM4ELMNACCR1CCR5CCR8
SCHEMBL23032849 0.79 CYP1A2 (0.47) KDM4ELMNACCR1CCR5CCR8
SCHEMBL1139044 0.79 HRH3 (0.57) KDM4ELMNACCR1CCR5CCR8
SCHEMBL11014433 0.79 CCR1 (0.44) KDM4ELMNACCR1CCR5CCR8
SCHEMBL9160556 0.79 CCR1 (0.61) KDM4ECCR1CCR5CCR8NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117963910-A Preparation of coal source humic acid porous material and application of porous material in separation and concentration of coal bed gas 太原理工大学 2024-05-03 CN disclosed
CN-116904239-A Natural gas dehydration material, preparation method and dehydration process thereof 昆山市恒安工业气体有限公司 2023-10-20 CN disclosed