Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4270992 | 0.84 | TDP1 (0.40) | GAATDP1KDM4EALDH1A1ALOX5 | |
| SCHEMBL2567549 | 0.82 | TNKS2 (0.35) | KMT2AGAAMEN1MAPK1THRB | |
| SCHEMBL11699836 | 0.81 | NOS2 (0.42) | KMT2AGAAMEN1MAPK1 | |
| SCHEMBL7349175 | 0.78 | MAPK1 (0.36) | KMT2AGAAMEN1MAPK1TDP1 | |
| SCHEMBL21590387 | 0.78 | CYP1A2 (0.36) | KMT2AGAAMEN1MAPK1THRB | |
| SCHEMBL16548415 | 0.77 | NOS2 (0.47) | HSD17B10KDM4EALDH1A1MAPTBACE1 | |
| SCHEMBL15277643 | 0.77 | SLC6A3 (0.39) | KMT2AGAAMEN1MAPK1THRB | |
| SCHEMBL11014433 | 0.75 | CCR1 (0.44) | MAPK1TDP1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL11030024 | 0.74 | ACHE (0.42) | KMT2AGAAMEN1MAPK1THRB | |
| SCHEMBL11732278 | 0.72 | PTGS2 (0.47) | MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085030-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED DIVINYL PYRIDINES, AND SUBSTITUTED DIVINYL PYRIDINES | CIBA-GEIGY AG (CH) | 1985-05-22 | — | — | EP | claimed |
| EP-0085030-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED DIVINYL PYRIDINES, AND SUBSTITUTED DIVINYL PYRIDINES | CIBA-GEIGY AG (CH) | 1985-05-22 | — | — | EP | disclosed |
| US-4477673-A | Process for the preparation of substituted divinylpyridines and novel substituted divinylpyridines | CIBA-GEIGY CORPORATION (US) | 1984-10-16 | — | — | US | disclosed |
| EP-0085030-A1 | Process for the preparation of substituted divinyl pyridines, and substituted divinyl pyridines | CIBA-GEIGY AG (CH) | 1983-08-03 | — | — | EP | disclosed |