Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11016671 | 1.00 | HSP90AA1 (0.73) | HSP90AA1KDM4EL3MBTL1KMT2ANPC1 | |
| SCHEMBL11019560 | 1.00 | HSP90AA1 (0.73) | HSP90AA1KDM4EL3MBTL1KMT2ANPC1 | |
| Caerulomycin A SCHEMBL29538011 | 0.85 | HSP90AA1 (1.00) | HSP90AA1KDM4EL3MBTL1NPC1RAB9A | |
| Caerulomycin A SCHEMBL597879 | 0.85 | HSP90AA1 (1.00) | HSP90AA1KDM4EL3MBTL1NPC1RAB9A | |
| Caerulomycin A SCHEMBL29479906 | 0.85 | HSP90AA1 (1.00) | HSP90AA1KDM4EL3MBTL1NPC1RAB9A | |
| Caerulomycin A SCHEMBL597880 | 0.85 | HSP90AA1 (1.00) | HSP90AA1KDM4EL3MBTL1NPC1RAB9A | |
| Caerulomycin A SCHEMBL11014579 | 0.85 | HSP90AA1 (1.00) | HSP90AA1KDM4EL3MBTL1NPC1RAB9A | |
| Caerulomycin K SCHEMBL21506982 | 0.82 | HSP90AA1 (0.69) | HSP90AA1KDM4EKMT2ANPC1RAB9A | |
| Caerulomycin K SCHEMBL29885287 | 0.82 | HSP90AA1 (0.69) | HSP90AA1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL14960439 | 0.80 | RAB9A (0.52) | HSP90AA1KDM4EL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159640-A1 | 4-Methoxy-2,2'-bipyridyl-6-aldoximes, process and intermediates for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-10-30 | — | — | EP | disclosed |
| EP-0159640-A1 | 4-Methoxy-2,2'-bipyridyl-6-aldoximes, process and intermediates for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-10-30 | — | — | EP | disclosed |