Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | CTH | P32929 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602459 | 0.88 | RAB9A (0.57) | RAB9ANPC1KDM4EHSP90AA1MAPK1 | |
| SCHEMBL21397879 | 0.88 | RAB9A (0.57) | RAB9ANPC1KDM4EHSP90AA1MAPK1 | |
| SCHEMBL20399817 | 0.87 | HSP90AA1 (0.61) | RAB9ANPC1KDM4EHSP90AA1MAPK1 | |
| SCHEMBL20399818 | 0.87 | HSP90AA1 (0.61) | RAB9ANPC1KDM4EHSP90AA1MAPK1 | |
| SCHEMBL20412773 | 0.87 | HSP90AA1 (0.61) | RAB9ANPC1KDM4EHSP90AA1MAPK1 | |
| SCHEMBL25399783 | 0.86 | RAB9A (0.54) | RAB9ANPC1KDM4EHSP90AA1P2RX7 | |
| SCHEMBL11014580 | 0.80 | HSP90AA1 (0.73) | RAB9ANPC1KDM4EHSP90AA1MAPK1 | |
| SCHEMBL11019560 | 0.80 | HSP90AA1 (0.73) | RAB9ANPC1KDM4EHSP90AA1MAPK1 | |
| SCHEMBL11016671 | 0.80 | HSP90AA1 (0.73) | RAB9ANPC1KDM4EHSP90AA1MAPK1 | |
| SCHEMBL22342567 | 0.78 | CTH (0.51) | RAB9ANPC1KDM4EHSP90AA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2171028-B1 | BIHETEROARYL METAL COMPLEXES AS BLEACH CATALYSTS | HENKEL AG & CO KGAA (DE) | 2013-05-22 | — | — | EP | disclosed |