Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 7/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11016694 | 0.99 | RAB9A (0.58) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11016594 | 0.97 | ALDH1A1 (0.61) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11016974 | 0.97 | ALDH1A1 (0.61) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11015017 | 0.97 | ALDH1A1 (0.61) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11017647 | 0.97 | ALDH1A1 (0.61) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11018932 | 0.97 | ALDH1A1 (0.61) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11018925 | 0.94 | RAB9A (0.57) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11016034 | 0.94 | RAB9A (0.54) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11019915 | 0.93 | ALDH1A1 (0.56) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL11017599 | 0.93 | ALDH1A1 (0.56) | RAB9ASMN1; SMN2MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158137-A2 | Pyrimidines | MERCK PATENT GmbH (DE) | 1985-10-16 | — | — | EP | disclosed |