Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015183 | 1.00 | THRB (0.41) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL10705069 | 0.82 | TSHR (0.39) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL10959455 | 0.82 | TSHR (0.39) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL11064205 | 0.79 | ELANE (0.41) | POLBNFE2L2MEN1KMT2AALOX5 | |
| SCHEMBL11064202 | 0.79 | ELANE (0.41) | POLBNFE2L2MEN1KMT2AALOX5 | |
| SCHEMBL15911020 | 0.78 | MAPT (0.48) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL11018514 | 0.77 | TSHR (0.33) | TSHRNFE2L2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11018511 | 0.77 | TSHR (0.33) | TSHRNFE2L2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13594741 | 0.77 | THRB (0.45) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL11015369 | 0.76 | POLB (0.37) | THRBPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031305-B1 | COMPOSITIONS CONTAINING ACRYLATE AND THEIR POLYMERISATION | CIBA-GEIGY AG (CH) | 1985-10-02 | — | — | EP | disclosed |
| US-4463169-A | Three component, carboxyl-containing compositions comprising dimercaptan | CIBA-GEIGY CORPORATION (US) | 1984-07-31 | — | — | US | disclosed |
| US-4439291-A | Acrylate-containing compositions and their polymerization | CIBA-GEIGY CORPORATION (US) | 1984-03-27 | — | — | US | disclosed |