Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | IAPP | P10997 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064202 | 1.00 | ELANE (0.41) | ELANENFE2L2KMT2AATMTRPM8 | |
| SCHEMBL10966783 | 0.80 | DHFR (0.36) | ELANEKMT2AATM | |
| SCHEMBL10966777 | 0.80 | DHFR (0.36) | ELANEKMT2AATM | |
| SCHEMBL11015183 | 0.79 | THRB (0.41) | ELANENFE2L2KMT2AATMMEN1 | |
| SCHEMBL11015181 | 0.79 | THRB (0.41) | ELANENFE2L2KMT2AATMMEN1 | |
| SCHEMBL10961953 | 0.78 | ELANE (0.31) | ELANE | |
| SCHEMBL10961955 | 0.78 | ELANE (0.31) | ELANE | |
| SCHEMBL11048493 | 0.78 | THRB (0.42) | NFE2L2KMT2ATRPM8MEN1KDM4E | |
| SCHEMBL11048489 | 0.78 | THRB (0.42) | NFE2L2KMT2ATRPM8MEN1KDM4E | |
| SCHEMBL11018514 | 0.76 | TSHR (0.33) | ELANENFE2L2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439291-A | Acrylate-containing compositions and their polymerization | CIBA-GEIGY CORPORATION (US) | 1984-03-27 | — | — | US | disclosed |