Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | HEXA | P06865 | 1/20 | 0.39 |
| ▸ | HEXB | P07686 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701770 | 0.85 | GRM5 (0.37) | KDM4ECYP3A4MAPTHPGDALDH1A1 | |
| SCHEMBL702351 | 0.82 | HSD11B1 (0.43) | DHFRKDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL702766 | 0.81 | HTR2A (0.39) | KDM4EMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL16401580 | 0.81 | PRMT5 (0.40) | KDM4ECYP3A4MAPTHPGDALDH1A1 | |
| SCHEMBL31518204 | 0.80 | KDM4E (0.38) | KDM4ECYP3A4MAPTHPGDALDH1A1 | |
| SCHEMBL16050773 | 0.79 | NR1H2 (0.42) | KDM4ECYP3A4MAPTHPGDALDH1A1 | |
| SCHEMBL16401560 | 0.78 | TDP1 (0.38) | KDM4ECYP3A4MAPTHPGDALDH1A1 | |
| SCHEMBL7544327 | 0.77 | HPGD (0.36) | KDM4ECYP3A4MAPTHPGDALDH1A1 | |
| SCHEMBL11742762 | 0.77 | LMNA (0.45) | KDM4ECYP3A4MAPTHPGDALDH1A1 | |
| SCHEMBL31518203 | 0.76 | CSNK2A2 (0.40) | KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063099-B1 | PROCESS FOR THE PREPARATION OF PHENYLETHYL TRIAZOLES | CIBA-GEIGY AG (CH) | 1985-11-27 | — | — | EP | disclosed |
| EP-0063099-A2 | Process for the preparation of phenylethyl triazoles | CIBA-GEIGY AG (CH) | 1982-10-20 | — | — | EP | disclosed |