Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015999 | 1.00 | PI4KB (0.69) | PI4KBHPGDPOLBMAPTXBP1 | |
| Viroxime SCHEMBL29365398 | 0.82 | PI4KB (1.00) | PI4KBMAPK14 | |
| Enviroxime SCHEMBL3585 | 0.82 | PI4KB (1.00) | PI4KBMAPK14 | |
| Zinviroxime SCHEMBL149064 | 0.82 | PI4KB (1.00) | PI4KBMAPK14 | |
| Viroxime SCHEMBL3586 | 0.82 | PI4KB (1.00) | PI4KBMAPK14 | |
| SCHEMBL11007999 | 0.82 | PI4KB (0.60) | PI4KBHPGDMAPTALDH1A1GFER | |
| SCHEMBL11008003 | 0.82 | PI4KB (0.60) | PI4KBHPGDMAPTALDH1A1GFER | |
| SCHEMBL11008032 | 0.81 | PI4KB (0.50) | PI4KBHPGDPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL11015148 | 0.81 | PI4KB (0.47) | PI4KBHPGDPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL11010087 | 0.80 | PI4KB (0.46) | PI4KBHPGDPOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4492708-A | Antiviral benzimidazoles | ELI LILLY AND COMPANY (US) | 1985-01-08 | — | — | US | claimed |
| EP-0111993-A2 | Improvements in or relating to benzimidazoles | ELI LILLY AND COMPANY (US) | 1984-06-27 | — | — | EP | claimed |
| US-4309258-A | Conversion of benzimidazole isomers | ELI LILLY AND COMPANY (US) | 1982-01-05 | — | — | US | disclosed |