Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11007999 | 1.00 | PI4KB (0.60) | PI4KBMAPK14HCAR1KMT2AMEN1 | |
| SCHEMBL11015999 | 0.82 | PI4KB (0.69) | PI4KBMAPK14KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11016000 | 0.82 | PI4KB (0.69) | PI4KBMAPK14KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11010165 | 0.81 | ABL1 (0.50) | PI4KBMAPK14HCAR1KMT2AMEN1 | |
| SCHEMBL11557178 | 0.81 | PI4KB (0.51) | PI4KBMAPK14KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11557174 | 0.81 | PI4KB (0.51) | PI4KBMAPK14KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11006351 | 0.78 | PI4KB (0.53) | PI4KBHCAR1ALDH1A1GFERACSS2 | |
| SCHEMBL11006353 | 0.78 | PI4KB (0.53) | PI4KBHCAR1ALDH1A1GFERACSS2 | |
| SCHEMBL11011359 | 0.75 | PDE4A (0.44) | PI4KBMAPK14HCAR1KMT2AMEN1 | |
| SCHEMBL11011358 | 0.75 | PDE4A (0.44) | PI4KBMAPK14HCAR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4492708-A | Antiviral benzimidazoles | ELI LILLY AND COMPANY (US) | 1985-01-08 | — | — | US | claimed |
| EP-0111993-A2 | Improvements in or relating to benzimidazoles | ELI LILLY AND COMPANY (US) | 1984-06-27 | — | — | EP | claimed |