Viroxime

Viroxime

SCHEMBL3586

CC(C)S(=O)(=O)n1c(N)nc2ccc(C(=NO)c3ccccc3)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PI4KB Q9UBF8 1/20 1.00
MAPK14 Q16539 19/20 0.52
CYP3A4 P08684 7/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinviroxime SCHEMBL149064 1.00 PI4KB (1.00) PI4KBMAPK14CYP3A4
Enviroxime SCHEMBL3585 1.00 PI4KB (1.00) PI4KBMAPK14CYP3A4
Viroxime SCHEMBL29365398 1.00 PI4KB (1.00) PI4KBMAPK14CYP3A4
Enviroxime SCHEMBL6475190 0.86 PI4KB (0.74) PI4KBMAPK14CYP3A4
SCHEMBL10906292 0.85 PI4KB (0.74) PI4KBMAPK14CYP3A4
SCHEMBL4837467 0.85 PI4KB (0.74) PI4KBMAPK14CYP3A4
SCHEMBL11073939 0.84 PI4KB (0.72) PI4KBMAPK14CYP3A4
SCHEMBL11149101 0.83 PI4KB (0.71) PI4KBMAPK14CYP3A4
Enviradene SCHEMBL10429409 0.83 PI4KB (0.71) PI4KBMAPK14CYP3A4
Enviradene SCHEMBL29367493 0.83 PI4KB (0.71) PI4KBMAPK14CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1957 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114432303-A Application of panobinostat in preparation of medicine for preventing and treating coronavirus 中国科学院深圳先进技术研究院 2022-05-06 CN claimed
CN-114432287-A Application of ITF2357 in preparation of medicine for preventing and treating coronavirus 中国科学院深圳先进技术研究院 2022-05-06 CN claimed
CN-114432305-A Application of CAY10603 in preparing medicine for preventing and treating coronavirus 中国科学院深圳先进技术研究院 2022-05-06 CN claimed
WO-2022088047-A1 APPLICATION OF ITF2357 IN PREPARATION OF DRUG FOR PREVENTING AND TREATING CORONAVIRUSES 中国科学院深圳先进技术研究院 2022-05-05 WO claimed
WO-2022088038-A1 APPLICATION OF CAY10603 IN PREPARATION OF DRUGS FOR PREVENTING AND TREATING CORONAVIRUS-RELATED DISEASES 中国科学院深圳先进技术研究院 2022-05-05 WO claimed
WO-2022088037-A1 APPLICATION OF SIRTINOL IN PREPARATION OF DRUG FOR PREVENTING AND TREATING CORONAVIRUS 中国科学院深圳先进技术研究院 2022-05-05 WO claimed
WO-2022088025-A1 APPLICATION OF PANOBINOSTAT IN PREPARING DRUG FOR PREVENTION AND TREATMENT OF CORONAVIRUS 中国科学院深圳先进技术研究院 2022-05-05 WO claimed
WO-2021253338-A1 USE OF ROMIDEPSIN IN PREVENTING AND TREATING CORONAVIRUS-RELATED DISEASES 中国科学院深圳先进技术研究院 2021-12-23 WO claimed
CN-113813366-A Application of romidepsin in preparation of medicine for preventing and treating novel anti-new-crown-pneumonia coronavirus 中国科学院深圳先进技术研究院 2021-12-21 CN claimed
US-20210299143-A1 USE OF ANTAGONISTS TO THE NUCLEAR STEROID RECEPTOR TO INHIBIT CORONAVIRUSES Spectral Analytics, Inc. (US) 2021-09-30 US claimed
US-4956351-A INCLUSION COMPLEXESOFVIRICIDES; RHINITIS; SUSTAINED RELEASE; NONIRRITATING TO MUCOUS MEMBRANE JANSSEN PHARMACEUTICA N.V. FRAME-543 (BE) 1990-09-11 US claimed
WO-1990006775-A1 A NOVEL NONPHOSPHOLIPID LIPOSOME COMPOSITION FOR SUSTAINED RELEASE OF DRUGS LIPOSOME TECHNOLOGY, INC. (US) 1990-06-28 WO claimed
EP-0207116-A1 IMPROVEMENTS RELATING TO THE TREATMENT CONTROL AND PREVENTION OF RHINOVIRUS INFECTIONS TYRRELL, David Arthur John (GB) 1987-01-07 EP claimed
WO-1986003412-A1 IMPROVEMENTS RELATING TO THE TREATMENT CONTROL AND PREVENTION OF RHINOVIRUS INFECTIONS TYRRELL DAVID ARTHUR JOHN 1986-06-19 WO claimed
EP-0047122-A2 Intranasal formulation ELI LILLY AND COMPANY (US) 1982-03-10 EP claimed
US-4309258-A Conversion of benzimidazole isomers ELI LILLY AND COMPANY (US) 1982-01-05 US claimed
US-4289782-A PARTICULARLY FOR INHIBITING GROWTH OF RHINOVIRUSES ELI LILLY AND COMPANY (US) 1981-09-15 US claimed
EP-0015339-A1 Separation of syn and anti 1-alkylsulfonyl-2-amino-5(6)hydroximinomethylbenzimidazole derivatives ELI LILLY AND COMPANY (US) 1980-09-17 EP claimed
US-4191832-A Separation of syn and anti oximes of 1-sulfonyl-2-aminobenzimidazoles ELI LILLY AND COMPANY (US) 1980-03-04 US claimed
US-4118742-A VIRICIDES ELI LILLY AND COMPANY (US) 1978-10-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210299143-A1 USE OF ANTAGONISTS TO THE NUCLEAR STEROID RECEPTOR TO INHIBIT CORONAVIRUSES NCOA1, NCOA2, NCOA3 PI4KB 3767/4885MAPK14 2822/4885CYP3A4 398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.