Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | ESRRB | O95718 | 2/20 | 0.33 |
| ▸ | ESRRA | P11474 | 2/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11009441 | 0.79 | ESR2 (0.50) | ESR2ESR1PDE10A | |
| SCHEMBL11010166 | 0.79 | ESR2 (0.50) | ESR2ESR1 | |
| SCHEMBL11007018 | 0.77 | ESR2 (0.54) | ESR2 | |
| SCHEMBL11014378 | 0.74 | MEN1 (0.49) | ESR2 | |
| SCHEMBL6180984 | 0.69 | ESR2 (0.49) | ESR2 | |
| SCHEMBL21236696 | 0.68 | KDM4E (0.45) | CSNK1A1CSNK1DCSNK1G2 | |
| SCHEMBL21236695 | 0.68 | APP (0.38) | CA2PIN1HRH3PDE10ACSNK1A1 | |
| SCHEMBL11386721 | 0.68 | CA12 (0.39) | ESR2CA12CA2CA3CA6 | |
| SCHEMBL11012636 | 0.67 | MEN1 (0.60) | — | |
| SCHEMBL1028464 | 0.67 | CA2 (0.58) | ESR2CA12CA2CA3CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4501898-A | Photographic development inhibitor (1H- or 2H-) indazolyl hydroquinone derivatives | FUJI PHOTO FILM CO., LTD. (JP) | 1985-02-26 | — | — | US | disclosed |
| US-4345024-A | A 3-INDAZOL-1 OR 2-YL HYDROQUINONE DERIVATIVE IN A PHOTOSENSITIVE SILVER HALIDE EMULSION; COLOR FILMS; BLACK AND WHITE PHOTOGRAPHY | FUJI PHOTO FILM CO., LTD. (JP) | 1982-08-17 | — | — | US | disclosed |