Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN6 | P29350 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 7/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11013012 | 0.79 | MAOB (0.47) | CNR2MAOBKDM4EALDH1A1HTT | |
| SCHEMBL4586812 | 0.77 | CA12 (0.46) | PTPN6PTPN11MAOBKDM4EALDH1A1 | |
| SCHEMBL30730276 | 0.73 | CNR2 (0.54) | CNR2MAOBALDH1A1HTTHPGD | |
| SCHEMBL1979700 | 0.72 | CNR2 (0.50) | CNR2MAOBALDH1A1L3MBTL1GAA | |
| SCHEMBL15204746 | 0.72 | PLCG1 (0.45) | CNR2MAOBMEN1KMT2AMAPT | |
| SCHEMBL30634283 | 0.72 | CYP3A4 (0.47) | MAOBKDM4EALDH1A1HTTTP53 | |
| SCHEMBL9423122 | 0.72 | MAOB (0.47) | CNR2MAOBKDM4EALDH1A1HPGD | |
| SCHEMBL25230166 | 0.70 | ABCB11 (0.42) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL30486599 | 0.70 | ABCB11 (0.42) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL29991034 | 0.70 | CNR2 (0.50) | CNR2MAOBMAPTNPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4555513-A | 1,2 Dihydro- and 1,2,3,4-tetrahydro quinolylacetic acids and analgesic use thereof | NIPPON ZOKI PHARMACEUTICAL CO. (JP) | 1985-11-26 | — | — | US | disclosed |
| EP-0083222-A1 | New quinolylacetic acid compounds and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1983-07-06 | — | — | EP | disclosed |