Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1163211 | 0.86 | ACSS2 (0.52) | ALOX15HTTALDH1A1KDM4ENPC1 | |
| SCHEMBL3603329 | 0.85 | ALOX15 (0.57) | ALOX15HTTALDH1A1NPC1RAB9A | |
| SCHEMBL12049554 | 0.80 | HTT (0.50) | ALOX15HTTALDH1A1KDM4ENPC1 | |
| SCHEMBL9423122 | 0.80 | MAOB (0.47) | MAOBALDH1A1KDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL3590574 | 0.79 | PABPC1 (0.49) | ALOX15HTTALDH1A1KDM4ENPC1 | |
| SCHEMBL28065794 | 0.79 | NPC1 (0.50) | ALOX15HTTALDH1A1KDM4ENPC1 | |
| SCHEMBL11016295 | 0.79 | PTPN6 (0.51) | MAOBHTTALDH1A1KDM4ENPC1 | |
| SCHEMBL21162763 | 0.77 | ALDH1A1 (0.49) | ALOX15HTTALDH1A1KDM4ENPC1 | |
| SCHEMBL1163248 | 0.77 | HTT (0.50) | ALOX15HTTALDH1A1KDM4ENPC1 | |
| SCHEMBL828067 | 0.75 | ALOX15 (0.71) | ALOX15HTTALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4555513-A | 1,2 Dihydro- and 1,2,3,4-tetrahydro quinolylacetic acids and analgesic use thereof | NIPPON ZOKI PHARMACEUTICAL CO. (JP) | 1985-11-26 | — | — | US | disclosed |
| EP-0083222-A1 | New quinolylacetic acid compounds and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1983-07-06 | — | — | EP | disclosed |