Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11017540 | 0.90 | KDM4E (0.49) | KDM4ERAB9ATP53RARBHSD17B10 | |
| SCHEMBL11015834 | 0.90 | KDM4E (0.49) | KDM4ERAB9ATP53RARBHSD17B10 | |
| SCHEMBL4950539 | 0.90 | KCNH2 (0.41) | KDM4ERAB9ATRPV1RARBHSD17B10 | |
| SCHEMBL4949286 | 0.90 | KCNH2 (0.41) | KDM4ERAB9ATRPV1RARBHSD17B10 | |
| SCHEMBL4947793 | 0.90 | KCNH2 (0.41) | KDM4ERAB9ATRPV1RARBHSD17B10 | |
| SCHEMBL11016961 | 0.89 | KDM4E (0.44) | KDM4ERAB9ATP53TRPV1RARB | |
| SCHEMBL11015800 | 0.89 | HSD17B10 (0.51) | KDM4ERAB9ATP53TRPV1RARB | |
| SCHEMBL4949276 | 0.88 | KCNH2 (0.40) | KDM4ERAB9ATRPV1HSD17B10TSHR | |
| SCHEMBL11013515 | 0.87 | KDM4E (0.49) | KDM4ERAB9ATP53TRPV1RARB | |
| SCHEMBL2767901 | 0.86 | KCNH2 (0.39) | KDM4ERAB9ATRPV1RARBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144013-A2 | Thienothiophene derivatives | MERCK PATENT GmbH (DE) | 1985-06-12 | — | — | EP | disclosed |