Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 3/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.31 |
| ▸ | PDE9A | O76083 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | PDE8A | O60658 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.30 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281236 | 0.90 | KDM4E (0.46) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL15083528 | 0.86 | KDM4E (0.49) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL7534659 | 0.82 | KDM4E (0.49) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL2113125 | 0.82 | KDM4E (0.49) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL4553693 | 0.82 | KDM4E (0.51) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL11130624 | 0.80 | KDM4E (0.48) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL23157264 | 0.80 | KDM4E (0.48) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL10788490 | 0.80 | KDM4E (0.49) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL17222397 | 0.78 | KDM4E (0.47) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| Pyridine SCHEMBL10491050 | 0.77 | KDM4E (0.47) | KDM4ETAS1R3TAS1R1TYMPPOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0145486-A2 | Microbiological process | GLAXO GROUP LIMITED (GB) | 1985-06-19 | — | — | EP | disclosed |