Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TYMP | P19971 | 8/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 3/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | PDE9A | O76083 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PDE8A | O60658 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15083528 | 0.91 | KDM4E (0.49) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL21828784 | 0.85 | TYMP (0.59) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL3821714 | 0.85 | TYMP (0.59) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL12714672 | 0.85 | TYMP (0.59) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL2281663 | 0.85 | TYMP (0.59) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL31556051 | 0.85 | TYMP (0.59) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL10788490 | 0.85 | KDM4E (0.49) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL29799112 | 0.84 | KDM4E (0.52) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL3820892 | 0.84 | KDM4E (0.56) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL26190487 | 0.83 | KDM4E (0.53) | KDM4ETYMPTAS1R3TAS1R1POLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2813512-B1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2021-03-31 | — | — | EP | disclosed |