Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.63 |
| ▸ | MAPT | P10636 | 9/20 | 0.63 |
| ▸ | HTT | P42858 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 7/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11017304 | 1.00 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPTHTTALDH1A1LMNA | |
| SCHEMBL15353953 | 0.91 | MAPT (0.70) | SMN1; SMN2MAPTHTTALDH1A1LMNA | |
| SCHEMBL4613912 | 0.84 | ALDH1A1 (0.50) | SMN1; SMN2MAPTHTTALDH1A1LMNA | |
| SCHEMBL4613914 | 0.84 | ALDH1A1 (0.50) | SMN1; SMN2MAPTHTTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL4827056 | 0.83 | ALDH1A1 (0.49) | SMN1; SMN2MAPTHTTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL4827050 | 0.83 | ALDH1A1 (0.49) | SMN1; SMN2MAPTHTTALDH1A1LMNA | |
| SCHEMBL5281467 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTHTTALDH1A1LMNA | |
| SCHEMBL5281464 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTHTTALDH1A1LMNA | |
| SCHEMBL17131996 | 0.78 | RAB9A (0.53) | SMN1; SMN2MAPTHTTALDH1A1LMNA | |
| SCHEMBL17107239 | 0.78 | RAB9A (0.53) | SMN1; SMN2MAPTHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055458-B1 | THIAZOLINE DERIVATIVES, THEIR PREPARATION AND USE AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-02-13 | — | — | EP | disclosed |
| US-4421757-A | ANTILIPORPROTEIN IN BLOOD | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-12-20 | — | — | US | disclosed |
| EP-0023964-B1 | PHENYLIMINOTHIAZOLINE DERIVATIVES, THEIR PREPARATION AND INTERMEDIATES THEREFOR, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR PRODUCTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-16 | — | — | EP | disclosed |
| US-4346088-A | ANTILIPEMICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-08-24 | — | — | US | disclosed |
| EP-0055458-A2 | Thiazoline derivatives, their preparation and use and pharmaceutical preparations containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-07-07 | — | — | EP | disclosed |
| EP-0023964-A1 | Phenyliminothiazoline derivatives, their preparation and intermediates therefor, pharmaceutical preparations containing them and their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-02-18 | — | — | EP | disclosed |