Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.53 |
| ▸ | ANPEP | P15144 | 5/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.46 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019714 | 0.88 | DPP4 (0.53) | DPP4ANPEPCRHBPCRHR2NR1H2 | |
| SCHEMBL11022123 | 0.86 | DPP4 (0.55) | DPP4ANPEPCRHBPCRHR2NR1H2 | |
| SCHEMBL11018579 | 0.85 | DPP4 (0.70) | DPP4ANPEPADORA2APABPC1HSPA1A | |
| SCHEMBL11021633 | 0.84 | DPP4 (0.50) | DPP4ANPEPCRHBPCRHR2NR1H2 | |
| SCHEMBL11021544 | 0.83 | DPP4 (0.52) | DPP4ANPEPCRHBPCRHR2MAPT | |
| SCHEMBL11018418 | 0.82 | DPP4 (0.51) | DPP4ANPEPCRHBPCRHR2NR1H2 | |
| SCHEMBL11018487 | 0.82 | LMNA (0.50) | DPP4ANPEPKDM4EMAPTPTPRC | |
| SCHEMBL11016927 | 0.81 | ANPEP (0.49) | DPP4ANPEPCRHBPCRHR2KDM4E | |
| SCHEMBL11019049 | 0.81 | AHR (0.53) | DPP4ANPEPKDM4EMAPTPDE4A | |
| SCHEMBL11019989 | 0.81 | DPP4 (0.49) | DPP4ANPEPCRHBPCRHR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |