Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.47 |
| ▸ | HPGD | P15428 | 14/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19717098 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL3282041 | 0.70 | LMNA (0.43) | ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL19717347 | 0.68 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL10815675 | 0.66 | KDM4E (0.56) | ALDH1A1HPGDKDM4ESMN1; SMN2ATM | |
| SCHEMBL11018436 | 0.65 | KDM4E (0.46) | ALDH1A1HPGDKDM4EKMT2AATM | |
| SCHEMBL10811815 | 0.65 | PDE3B (0.51) | ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL11024172 | 0.65 | KDM4E (0.42) | ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL13075980 | 0.64 | ATM (0.68) | ALDH1A1HPGDKDM4EATMGAA | |
| SCHEMBL11023239 | 0.64 | KDM4E (0.41) | ALDH1A1HPGDKDM4EATMGAA | |
| SCHEMBL11026225 | 0.64 | KDM4E (0.45) | ALDH1A1HPGDKDM4EATMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |