Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | HTR2B | P41595 | 3/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10854601 | 0.98 | HTR2A (0.49) | HTR2AHTR2CHTR2BHRH3SSTR1 | |
| Hydrochloric Acid SCHEMBL10854594 | 0.98 | HTR2A (0.49) | HTR2AHTR2CHTR2BHRH3SSTR1 | |
| SCHEMBL11021080 | 0.81 | PTGS2 (0.39) | HTR2A | |
| SCHEMBL11022069 | 0.80 | SMN1; SMN2 (0.43) | HTR2AHTR2CHTR2BHRH3SMN1; SMN2 | |
| SCHEMBL11018524 | 0.80 | HTR2A (0.44) | HTR2AHTR2CHTR2BHRH3KMT2A | |
| Hydrochloric Acid SCHEMBL10855552 | 0.80 | PTGS2 (0.38) | HTR2A | |
| Hydrochloric Acid SCHEMBL10857042 | 0.80 | KCNH2 (0.44) | HTR2AHTR2CHTR2BHRH3 | |
| Hydrochloric Acid SCHEMBL10857036 | 0.80 | KCNH2 (0.44) | HTR2AHTR2CHTR2BHRH3 | |
| Hydrochloric Acid SCHEMBL10855338 | 0.79 | SRD5A2 (0.38) | HTR2AALDH1A1MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL10850138 | 0.78 | HTR2A (0.44) | HTR2AHTR2CHTR2BHRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0139296-A2 | Dihydroisoquinoline derivatives | BEECHAM GROUP PLC (GB) | 1985-05-02 | — | — | EP | claimed |