Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.56 |
| ▸ | RAF1 | P04049 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 5/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15121199 | 0.85 | ALDH1A1 (0.70) | ALDH1A1MAPK14RAF1CNR2MAPK13 | |
| SCHEMBL10804133 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPK14RAF1CNR2MAPK13 | |
| SCHEMBL2635371 | 0.80 | ALDH1A1 (0.71) | ALDH1A1MAPK14RAF1CNR2MAPK13 | |
| SCHEMBL14379225 | 0.79 | ALDH1A1 (0.74) | ALDH1A1MAPK14RAF1CNR2MAPK13 | |
| SCHEMBL18232996 | 0.79 | ALDH1A1 (0.74) | ALDH1A1MAPK14RAF1CNR2MAPK13 | |
| SCHEMBL11050897 | 0.78 | ALDH1A1 (0.72) | ALDH1A1MAPK14RAF1CNR2MAPK13 | |
| SCHEMBL18232987 | 0.77 | MAPK14 (0.76) | ALDH1A1MAPK14RAF1MAPK13NTRK1 | |
| SCHEMBL11114594 | 0.77 | ALDH1A1 (0.67) | ALDH1A1MAPK14RAF1CNR2MAPK13 | |
| SCHEMBL9893018 | 0.77 | ALDH1A1 (0.71) | ALDH1A1MAPK14RAF1CNR2MAPK13 | |
| SCHEMBL9892786 | 0.76 | ALDH1A1 (0.65) | ALDH1A1MAPK14RAF1CNR2MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144098-A1 | Cyclic ureas of isoxazole | SHIONOGI & CO., LTD. (JP) | 1985-06-12 | — | — | EP | disclosed |