Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.53 |
| ▸ | GABRP | O00591 | 3/20 | 0.44 |
| ▸ | GABRD | O14764 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.44 |
| ▸ | GABRE | P78334 | 3/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11017703 | 0.79 | PTGS2 (0.76) | LMNAPTGS2MALT1KDM4ESMN1; SMN2 | |
| SCHEMBL5205230 | 0.79 | LMNA (0.46) | LMNAPTGS2GABRPGABRDGABRA1 | |
| SCHEMBL11019585 | 0.76 | PTGS2 (0.67) | LMNAPTGS2MALT1KDM4ESMN1; SMN2 | |
| SCHEMBL11019135 | 0.76 | PTGS2 (0.67) | LMNAPTGS2MALT1KDM4ESMN1; SMN2 | |
| SCHEMBL5202264 | 0.73 | PTGS2 (0.43) | PTGS2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11020712 | 0.71 | SMN1; SMN2 (0.53) | LMNAPTGS2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL5273708 | 0.70 | PTGS2 (0.67) | PTGS2CYP2C9PTGS1 | |
| SCHEMBL5201440 | 0.69 | PTGS2 (0.49) | PTGS2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3874666 | 0.69 | LMNA (0.54) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13239889 | 0.68 | MALT1 (0.46) | PTGS2MALT1CYP3A4KMT2ANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155486-A1 | 1,3,5-Trisubstituted 1,2,4-triazole derivatives, process for their preparation and medicinal preparations containing them | ALKALOIDA VEGYéSZETI GYáR (HU) | 1985-09-25 | — | — | EP | disclosed |