Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3976296 | 0.74 | HTR1A (0.41) | HTR7HTR1A | |
| SCHEMBL928949 | 0.70 | HTR7 (0.47) | HTR7HTR1APLD1KDM4ELMNA | |
| Dipyridyl SCHEMBL11217314 | 0.69 | HTR7 (0.53) | HTR7HTR1APLD1KDM4ELMNA | |
| SCHEMBL4858561 | 0.69 | NISCH (0.36) | KDM4ECYP1A2NISCHSMN1; SMN2ALDH1A1 | |
| SCHEMBL10298806 | 0.69 | HTR7 (0.46) | HTR7HTR1APLD1KDM4ELMNA | |
| Dipyridyl SCHEMBL29189121 | 0.68 | KDM4E (0.70) | HTR7HTR1APLD1KDM4ELMNA | |
| Dipyridyl SCHEMBL8655605 | 0.65 | KDM4E (0.93) | KDM4ELMNACYP1A2POLBCCR1 | |
| Dipyridyl SCHEMBL6885910 | 0.65 | KDM4E (0.93) | KDM4ELMNACYP1A2POLBCCR1 | |
| Dipyridyl SCHEMBL29072852 | 0.65 | KDM4E (0.93) | KDM4ELMNACYP1A2POLBCCR1 | |
| Dipyridyl SCHEMBL11767839 | 0.65 | KDM4E (0.93) | KDM4ELMNACYP1A2POLBCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160910-A2 | 7-Deazapurine derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1985-11-13 | — | — | EP | disclosed |