Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | GAA | P10253 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10678325 | 0.88 | NPC1 (0.59) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL17123531 | 0.78 | MAPT (0.67) | IDO1SMN1; SMN2NPSR1MAPTNPC1 | |
| SCHEMBL11020618 | 0.78 | MAPT (0.67) | IDO1SMN1; SMN2NPSR1MAPTNPC1 | |
| SCHEMBL29858587 | 0.78 | IDO1 (0.70) | IDO1SMN1; SMN2NPSR1MAPTNPC1 | |
| SCHEMBL3408807 | 0.78 | IDO1 (0.70) | IDO1SMN1; SMN2NPSR1MAPTNPC1 | |
| SCHEMBL24707373 | 0.76 | IDO1 (0.55) | IDO1SMN1; SMN2NPSR1MAPTNPC1 | |
| SCHEMBL10672271 | 0.75 | NPC1 (0.55) | SMN1; SMN2MAPTNPC1RAB9AGAA | |
| SCHEMBL2137684 | 0.74 | IDO1 (1.00) | IDO1SMN1; SMN2NPSR1MAPTNPC1 | |
| SCHEMBL13284915 | 0.74 | IDO1 (0.64) | IDO1SMN1; SMN2NPSR1MAPTNPC1 | |
| SCHEMBL12963415 | 0.72 | IDO1 (0.60) | IDO1SMN1; SMN2NPSR1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160173-A1 | Benzothiazole derivatives, processes for their production and medicaments containing them | LUDWIG HEUMANN & CO GMBH (DE) | 1985-11-06 | — | — | EP | disclosed |